ISTO's Cell-Based Platform Technology
In 1997, while ISTO scientists were studying the possibility of regenerating injured cartilage, they discovered that juvenile cartilage cells produce hyaline cartilage much more effectively than adult cartilage cells in the laboratory. This observation led to the development of a patented process for expanding these cells to create commercial quantities of viable cartilage cells for clinical applications.
ISTO is currently enrolling subjects in the Phase III DeNovo ET clinical trial. For more information about this study, please click here or go to www.repairmyknee.com.
ISTO scientists have also developed an injectable formulation of these cells to be used in the spine to repair damage to the disc nucleus. A safety trial was initiated in March 2010.
ISTO's Cartilage Technology
