DeNovo®ET Living Cartilage Implant

DeNovo ET is a scaffold-free living cartilage implant designed as an off-the-shelf product to repair and regenerate damaged knee cartilage. ISTO Technologies uses a patented, juvenile cell-based technology to produce DeNovo ET implants. Juvenile cartilage cells have far superior regenerative properties than adult cartilage cells (1).

ISTO’s patented cell-based technology harnesses the natural healing power of juvenile cartilage cells to create a living cartilage implant. The resulting implant exhibits biochemical properties similar to those of articular cartilage found in young, healthy joints (1).

 

DeNovo ET offers distinct advantages

  • Patented juvenile cell-based technology that has proved to have superior regenerative properties to adult
    cartilage cells
  • Living juvenile cartilage implant may offer better integration of cartilage into host tissue
  • Scaffold-free hyaline cartilage is similar to cartilage in young, healthy joints
  • Single-step application procedure; one surgery incurs less trauma.
  • Easy to use; implant glues into place
  • Patented cell expansion technology allows for scalable implant production to meet worldwide demand

DeNovo® ET is a registered trademark of Zimmer Holdings, Inc. This product is in Phase I/II Clinical Trials. 

 

 





 

 

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